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If you miss a dose of rabeprazole delayed-release tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Controlled studies for maintenance therapy have not extended beyond 12 months. Increased INR and prothrombin time in patients receiving PPIs, including rabeprazole, and warfarin concomitantly.

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Combination Treatment with Amoxicillin and Clarithromycin: In clinical trials using combination therapy with Rabeprazole plus amoxicillin and clarithromycin RAC no adverse reactions unique to this drug combination were observed. The brands listed are trademarks of their respective owners and are not trademarks of Aurobindo Pharma Limited. Keane WF, Swan SK, Grimes I et al. Rabeprazole: pharmacokinetics and tolerability in patients with stable, end-stage renal failure. J Clin Pharmacol.

Health Initiative Arch Intern Med

Dexmethylphenidate: Proton Pump Inhibitors may increase the absorption of Dexmethylphenidate. Specifically, proton pump inhibitors may interfere with the normal release of drug from the extended-release capsules Focalin XR brand which could result in both increased absorption early and decreased delayed absorption. Pathological hypersecretory conditions tablets only: Long-term treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome in adults. Stool antigen testing may be done to help support a diagnosis of H. pylori infection or to find out whether treatment for an H. pylori infection has been successful.

There may be new information

Tell your doctor if your condition persists or worsens. The risk of side effects goes up over time. Ask your doctor how long you should take this medication. You should not use this medication if you are allergic to rabeprazole or to similar medicines such as Prevacid Nexium Prilosec, Zegerid or Protonix. In a single dose study of 10 patients with mild to moderate hepatic impairment Child-Pugh Class A and B, respectively who were administered a single 20 mg dose of Rabeprazole sodium delayed-release tablets, AUC 0-24 was approximately doubled, the elimination half-life was 2- to 3-fold higher, and total body clearance was decreased to less than half compared to values in healthy men.



Dexilant, Kapidex and levolansoprazole

If you have any questions about probiotic, please talk with your doctor, pharmacist, or other health care provider. Magnesium levels prior to initiation of therapy and periodically thereafter in patients on long-term treatment or those taking digoxin, diuretics, or other drugs that cause hypomagnesemia; susceptibility testing recommended in patients who fail H. pylori eradication regimen. AstraZeneca, Nexium esomeprazole magnesium delayed-release capsules prescribing information. Wilmington, DE; 2001 Aug. Broeren MA, Geerdink EA, Vader HL et al. Hypomagnesemia induced by several proton-pump inhibitors. Ann Intern Med. You may feel some discomfort as the tube is being placed, but it takes only about a minute to place the tube. Most patients quickly adjust to the tube's presence. and are possible when the tube is being placed, but are rare. Norgard NB, Mathews KD, Wall GC. Drug-drug interaction between clopidogrel and the proton pump inhibitors. Ann Pharmacother. GlaxoSmithKline. Lanoxin digoxin tablets prescribing information. Research Triangle Park, NC; 2009 Aug. This is not a complete list of possible side effects. If you notice other effects, contact your doctor or pharmacist. Concomitant administration of clarithromycin with other drugs can lead to serious adverse reactions, including potentially fatal arrhythmias, and are contraindicated. Patients with Barrett's esophagus typically need PPI drugs to reduce acid. See Drug Interactions in prescribing information for amoxicillin. The plasma half-life of rabeprazole ranges from 1 to 2 hours. Rabeprazole after a single 20 mg dose of Rabeprazole sodium delayed-release tablets when compared to 10 healthy subjects. Your doctor may prescribe antibiotic medicines with Rabeprazole sodium delayed-release tablets to help treat a stomach infection and heal stomach duodenal ulcers that are caused by bacteria called H. pylori. The dosage and length of treatment are based on your medical condition and response to treatment. In children, the dosage is also based on weight.



Guide provided separately to each patient

Tarceva erlotinib US prescribing information. Genentech, Inc. Check with your pharmacist about how to dispose of unused medicine. Atazanavir: See prescribing information for atazanavir for dosing information. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. Targownik LE, Lix LM, Metge CJ et al. Use of proton pump inhibitors and risk of osteoporosis-related fractures. CMAJ. No patients developed amoxicillin-resistant H. pylori during therapy. Hirai M, Azuma T, Ito S et al. A proton pump inhibitor, E3810, has antibacterial activity through niding to Helicobacter pylori. J Gastroenterol. Results from the urea breath test or a stool test are usually available within a few hours. Results from a blood test are usually available within 24 hours. Results from biopsy samples obtained by are usually available within 48 hours. Results from a biopsy sample that is cultured can take up to 10 days. Talk to your doctor about any concerns you have about the need for the test, its risks, how it will be done, or what the results may mean. To help you understand the importance of this test, fill out the What is a document? Discuss specific use of drug and side effects with patient as it relates to treatment. HCAHPS: During this hospital stay, were you given any medicine that you had not taken before? Patients with persistent H. pylori infection following Rabeprazole, amoxicillin, and clarithromycin therapy will likely have clarithromycin resistant clinical isolates. Therefore, clarithromycin susceptibility testing should be done when possible. If resistance to clarithromycin is demonstrated or susceptibility testing is not possible, alternative antimicrobial therapy should be instituted. CYP2C8 Substrates: CYP2C8 Inhibitors Moderate may decrease the metabolism of CYP2C8 Substrates. Rabeprazole sodium delayed-release tablets are indicated for maintaining healing and reduction in relapse rates of heartburn symptoms in patients with erosive or ulcerative gastroesophageal reflux disease GERD Maintenance. Controlled studies do not extend beyond 12 months. Take this medication by as directed by your doctor. Dosage is based on your medical condition, age, and response to treatment. Your dose may be gradually increased until the drug starts working well. Follow your doctor's instructions closely to reduce the risk of side effects. persantine



What are the possible side effects of rabeprazole

Posaconazole: Proton Pump Inhibitors may decrease the serum concentration of Posaconazole. If you are taking a liquid product, use a medication-measuring device to carefully measure the dose. Do not use a household spoon. Some liquid products need to be shaken before each dose. Some products that contain need to be placed under the and held there before swallowing. Follow label directions carefully to get the most benefit. Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. Important: The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, blogs, or WebMD Answers are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Hug G, McGraw CA, Bates SR, et al. Reduction of serum carnitine concentrations during anticonvulsant therapy with phenobarbital, valproic acid, phenytoin, and carbamazepine in children. Antacids may be used concomitantly as needed for pain relief. fibo.info furosemide



Inhibitors PPIs with Methotrexate

Gilard M, Cornily JC, Boschat J. Initial assessment of clinical impact of a drug interaction between clopidogrel and proton pump inhibitors. JACC. Tell your doctor if you cannot swallow tablets whole. You may need a different medicine. Read the Medication Guide and the Patient Information Leaflet if available from your pharmacist before you start taking rabeprazole and each time you get a refill. If you have any questions, ask your doctor or pharmacist. PPI therapy appropriate to the condition being treated. Hiatal hernia surgery can be performed either by opening the abdominal cavity or laparoscopically. During laparoscopic surgery, five or six small 5 to 10 millimeter incisions are made in the abdomen. The laparoscope and surgical instruments are inserted through these incisions. The surgeon is guided by the laparoscope, which transmits a picture of the internal organs on a monitor. The advantages of laparoscopic surgery include smaller incisions, less risk of infection, less pain and scarring, and a more rapid recovery. Esophageal cancer develops through a sequence of changes in the cells of the esophagus known as dysplasia. Dysplasia can only be detected by a biopsy. Patients with Barrett's esophagus should talk to their doctors about having regular screening exams to detect cancer at an early and potentially curable stage. Do I need a prescription for rabeprazole? Importance of advising patients that use of multiple daily doses of the drug for an extended period of time may increase the risk of fractures of the hip, wrist, or spine. Rabeprazole or any of the other ingredients in Rabeprazole sodium delayed-release tablets. See the end of this Medication Guide for a complete list of ingredients in Rabeprazole sodium delayed-release tablets. Give you a capsule or some water to swallow that contains tagged or radioactive material. Distributed and Marketed by FSC Laboratories, Inc. Zegerid OTC is not intended for the immediate relief of heartburn. Prevention of GI bleeding in patients receiving antiplatelets. Lee, D. U. Inhibitory effects of the fragrance inhalation of essential oil from Acorus gramineus on central nervous system. Biol Pharm. Some medical conditions may interact with rabeprazole delayed-release tablets. Manikandan, S. and Devi, R. S. Antioxidant property of alpha-asarone against noise-stress-induced changes in different regions of rat brain.



Who should not take ACIPHEX Sprinkle?

If you take rabeprazole to treat duodenal ulcers, take the medicine after a meal. If you take rabeprazole to prevent ulcers caused by Helicobacter pylori, take the medicine with food. If you take rabeprazole for any other condition, you may take the medicine with or without food. This medicine can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. See “What is the most important information I should know about Rabeprazole sodium delayed-release tablets? Capecitabine: Proton Pump Inhibitors may diminish the therapeutic effect of Capecitabine. You may feel a temporary soreness in your throat. Lozenges or gargling with salt water may help. Dabigatran Etexilate: Proton Pump Inhibitors may decrease serum concentrations of the active metabolites of Dabigatran Etexilate. lanoxin



Rabeprazole side effects

Its demethylated-metabolite was also positive in the Ames test. Most urea breath tests now use tagged carbon rather than radioactive carbon. If you are pregnant, the radioactive urea breath test for H. pylori is not usually done, because the radiation could harm your child. KAPILA, K. Anticonvulsant, antiveratrinic and antiarrhythmic actions of Acorus calamus Linn. When should I take an antacid vs. a FamotidinePepcid-AC or Omeprazole Prilosec-like product? Severe myalgia from an interaction between treatments with pantoprazole and methotrexate. CULLUMBINE, H. Studies on Acorus calamus. II. Investigation of volatile oil. J Pharm. If you have questions about how to schedule your medicines, ask your pharmacist. Older adults may be more sensitive to the side effects of this drug, especially loss of coordination and drowsiness. These side effects can increase the risk of falling. The antiplatelet activity of clopidogrel may be decreased. Avoid coadministration unless there is a specific indication for a proton pump inhibitor. H 2 receptor antagonists eg, ranitidine may be a safer alternative. The American College of Gastroenterology recommends 10 to 14 days of therapy triple or quadruple for eradication of H. pylori Chey 2007. The tube does not interfere with your breathing. You are seated while the tube is inserted. The tube is connected to a machine that records the of the esophageal muscles on a graph. Patients using this drug to treat gastroesophageal reflux disease symptoms for longer than 6 months should be further reevaluated. But most people with H. pylori in their digestive systems do not develop ulcers. The pH of your GI tract needs to be acidic for your cancer medicine to dissolve and be absorbed. H2 blockers and proton pump inhibitors change the pH acidity your GI tract. Use with caution in patients with severe hepatic impairment. purchase lisinopril 5mg tablets



How to take rabeprazole

Gilard M, Arnaud B, Cornily JC et al. Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin. JACC. Fractures: Increased incidence of osteoporosis-related bone fractures of the hip, spine, or wrist may occur with proton pump inhibitor PPI therapy. If you need to use an antacid while on dasatinib or nilotinib, take the antacid at least 2 hours before or 2 hours after your dasatinib or nilotinib. Rabeprazole is used short-term to treat symptoms of gastroesophageal reflux disease GERD in adults and children who are at least 1 year old. This test can show if you have an H. pylori infection. It can also be used to see if treatment has worked to get rid of H. pylori. Prolonged binding to gastric parietal proton pump enzyme. Rabeprazole sodium delayed-release tablets are contraindicated in patients with known hypersensitivity to Rabeprazole, substituted benzimidazoles, or to any component of the formulation. It is unknown if this medication passes into breast milk. However, similar drugs pass into breast milk. The effects on a nursing infant are unknown. Consult your doctor before breast-feeding. Mild-to-moderate impairment Child-Pugh class A or B: No dosage adjustment necessary. Use the lowest effective dosage and shortest duration of therapy appropriate for the patient's clinical condition. Rabeprazole may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication. Avoid administration of PPIs for longer than medically indicated. If signs or symptoms consistent with CLE or SLE are noted in patients receiving Rabeprazole sodium delayed-release tablets, discontinue the drug and refer the patient to the appropriate specialist for evaluation. Most patients improve with discontinuation of the PPI alone in 4 to 12 weeks. Swallow rabeprazole delayed-release tablets whole. Do not break, crush, or chew before swallowing. Metabolism: Rabeprazole is extensively metabolized. What are the possible side effects of rabeprazole Aciphex?



PPIs can not be avoided

Rude MK, Chey WD. Proton-pump inhibitors, clopidogrel, and cardiovascular adverse events: fact, fiction, or something in between? Compared to placebo, 10 mg, 20 mg, and 40 mg of Rabeprazole sodium delayed-release tablets, administered once daily for 7 days significantly decreased intragastric acidity with all doses for each of four meal-related intervals and the 24-hour time period overall. In this study, there were no statistically significant differences between doses; however, there was a significant dose-related decrease in intragastric acidity. The ability of Rabeprazole to cause a dose-related decrease in mean intragastric acidity is illustrated below. Importance of informing patients of other important precautionary information. 1 See Cautions. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tablets: When used for the treatment of duodenal ulcers, administer after a meal; when used for the eradication of Helicobacter pylori, administer with the morning and evening meals. Srimal, R. C. Protective effect of acorus calamus against acrylamide induced neurotoxicity. Phytother. Because clinical trials are conducted under varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. In patients who fail therapy, susceptibility testing should be done. femara purchase online payment canada



Practice Guidelines Am J Gastroenterol

Dekkers CP, Beker JA, Thjodleifsson B et al. Comparison of rabeprazole 20 mg versus omperazole 20 mg in the treatment of active duodenal ulcer: a European multicentre study. Aliment Pharmacol Ther. If you are taking this product on a regular schedule and miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Rabeprazole may also be used for purposes not listed in this medication guide. What is the most important information I should know about rabeprazole? Before having surgery, tell your doctor or dentist about all the products you use including prescription drugs, nonprescription drugs, and herbal products. Corley DA, Kubo A, Zhao W et al. Proton pump inhibitors and histamine-2 receptor antagonists are associated with hip fractures among at-risk patients. Gastroenterology. The stool sample contains H. pylori antigens. Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest or throat; swelling of the mouth, face, lips, or tongue; unusual hoarseness; bloody or watery stools; bone pain; chest pain; dizziness; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; involuntary muscle movements; joint or muscle aches or pain; red, swollen, blistered, or peeling skin; seizures; severe or persistent diarrhea, nausea, or vomiting; severe or persistent stomach or back pain; stomach cramps; swelling of the hands, ankles, or feet; symptoms of kidney problems eg, not able to pass urine, change in the amount of urine produced, blood in the urine, a big weight gain; symptoms of liver problems eg, dark urine, loss of appetite, pale stools, unusual nausea, yellowing of the skin or eyes; tremors; unexplained weight loss; unusual bruising or bleeding; unusual tiredness or weakness. Calamus might increase stomach acid. By increasing stomach acid, calamus might decrease the effectiveness of some medications that decrease stomach acid, called H2-Blockers. Some medications that decrease stomach acid include cimetidine Tagamet ranitidine Zantac nizatidine Axid and famotidine Pepcid. Minerals with ADEK, Folate, Iron. Specifically, the absorption of iron may be decreased. Discuss the risks and benefits with your doctor. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Pharmacokinetic and adverse effect profiles similar to those in adults. Wrap an elastic band around your upper arm to stop the flow of blood. This makes the veins below the band larger so it is easier to put a needle into the vein. Rabeprazole sodium delayed-release tablets should not be used in children under 12 years of age. cheap microzide sales



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Rabeprazole sodium delayed-release tablets, amoxicillin, and clarithromycin for 3, 7, or 10 days vs. omeprazole, amoxicillin, and clarithromycin for 10 days. Therapy consisted of Rabeprazole 20 mg twice daily, amoxicillin 1000 mg twice daily, and clarithromycin 500 mg twice daily RAC or omeprazole 20 mg twice daily, amoxicillin 1000 mg twice daily, and clarithromycin 500 mg twice daily OAC. Possible increased risk of Clostridium difficile infection; importance of contacting clinician if persistent watery stools, abdominal pain, and fever occur. Read the Guide provided by your before you start taking and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Atrophic gastritis: Long-term omeprazole therapy has caused atrophic gastritis by biopsy; this may also occur with rabeprazole. Lisi, D. M. Availability and uses of FDA unsafe herbs on the Internet. When used in combination with clarithromycin and amoxicillin for treatment of H. pylori infection and duodenal ulcer disease, take all 3 drugs twice daily with morning and evening meals. Inactive ingredients of the 20 mg tablet are crospovidone, diacetylated monoglycerides, ethyl cellulose, ferric oxide yellow, hydroxypropyl cellulose, hypromellose phthalate, low substituted hydroxypropyl cellulose, magnesium stearate, mannitol, magnesium oxide, magnesium hydroxide, sodium carbonate, talc, and titanium dioxide. The tablets are printed with edible ink containing black iron oxide and shellac. Known hypersensitivity to rabeprazole or substituted benzimidazoles, or to any component of the formulation. The breath sample is collected when you blow into a balloon or blow bubbles into a bottle of liquid. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Some people who take proton pump inhibitor PPI medicines, including Rabeprazole sodium delayed-release tablets, may develop a kidney problem called acute interstitial nephritis that can happen at any time during treatment with Rabeprazole sodium delayed-release tablets. Call your doctor if you have a decrease in the amount that you urinate or if you have blood in your urine. B12 malabsorption can occur during treatment with these agents, particularly proton pump inhibitors, although the likelihood of developing clinically significant deficiency over time is unknown. Kwok CS, Arthur AK, Anibueze CI et al. Risk of Clostridium difficile Infection With Acid Suppressing Drugs and Antibiotics: Meta-Analysis. Am J Gastroenterol.



C 1 Protect from moisture

Hypersecretory conditions including Zollinger-Ellison Syndrome: Tablets: Oral: Initial: 60 mg once daily; adjust dose to patient needs some may require divided doses. Doses as high as 100 mg once daily and 60 mg twice daily have been used; continue as long as clinically indicated. Keep Rabeprazole sodium delayed-release tablets and all medicines out of the reach of children. PPIs was subacute CLE SCLE and occurred within weeks to years after continuous drug therapy in patients ranging from infants to the elderly. Generally, histological findings were observed without organ involvement. RxList is part of the WebMD Health Network. The opinions expressed in the WebMD User Reviews are solely those of the User, who may or may not have medical or scientific training, and do not represent the opinions of WebMD. These member reviews have not been reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other purpose except for compliance with our Terms and Conditions. These may be signs of a more serious condition. See your doctor. Parab, R. S. and Mengi, S. A. Hypolipidemic activity of Acorus calamus L. in rats. Dandiya, P. C. and SHARMA, J. D. Studies on Acorus calamus. V. Pharmacological actions of asarone and beta-asarone on central nervous system. Amodiaquine: CYP2C8 Inhibitors may increase the serum concentration of Amodiaquine. Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor. Japanese men were approximately 50 to 60% greater than values derived from pooled data from healthy men in the United States. Bock, R. The cox2 locus of the primitive angiosperm plant Acorus calamus: molecular structure, transcript processing and RNA editing. Mol. The Importance of DMOZ or Other Directories? Yang YX, Metz DC. Safety of proton pump inhibitor exposure. Gastroenterology. Remember that your doctor has prescribed this because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication not have serious side effects. ACX 5mg” on the capsule body. Side Effects List Aciphex side effects by likelihood and severity. where to buy reductil for babies



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Rabeprazole ingredients


Do not swallow the capsule whole

Bucher, M. and Kuhlemeier, C. Long-term anoxia tolerance. Rabeprazole sodium delayed-release tablets compared to placebo over the 4 weeks of study in Study RAB-USA-2 47% vs. 23% and Study RAB-USA-3 52% vs. 28%. PP population and -9. Mitotane: May decrease the serum concentration of CYP3A4 Substrates. Management: Doses of CYP3A4 substrates may need to be adjusted substantially when used in patients being treated with mitotane. Rabeprazole sodium delayed-release tablets may help your acid-related symptoms, but you could still have serious stomach problems. Talk with your doctor. renova

ACIPHEX Sprinkle for a long period of time

The remainder of the dose was recovered in the feces. Proton pump inhibitors may decrease the ability of your kidneys to remove methotrexate from your body. For all other indications Rabeprazole sodium delayed-release tablets can be taken with or without food. It inhibits acid transport in porcine gastric vesicles with a half-life of 90 seconds. Please refer to the for information on shortages of one or more of these preparations.

About rabeprazole

Rabeprazole sodium delayed-release tablets, in combination with amoxicillin and clarithromycin as a three drug regimen, are indicated for the treatment of patients with H. pylori infection and duodenal ulcer disease active or history within the past 5 years to eradicate H. pylori. Eradication of H. pylori has been shown to reduce the risk of duodenal ulcer recurrence. Available studies have not shown an increased risk of major birth defects following maternal use of proton pump inhibitors during pregnancy; however, information specific to rabeprazole is limited Pasternak 2010; most information available for omeprazole. When treating GERD in pregnancy, PPIs may be used when clinically indicated Katz 2013.

Rabeprazole forms and strengths

Treatment for longer than 12 weeks is not recommended. Dhalla, N. S. Investigations on the mechanism of potentiation of barbiturate hypnosis by hersaponin, acorus oil, reserpine and chlorpromazine. Arch Int Pharmacodyn. Replace the container cap and label the container with your name, your doctor's name, and the date the sample was collected. Short-term treatment in healing and symptomatic relief of duodenal ulcers and erosive or ulcerative GERD; maintaining healing and reducing relapse rates of heartburn symptoms in patients with erosive or ulcerative GERD; treatment of daytime and nighttime heartburn and other symptoms associated with GERD; long-term treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome; in combination with amoxicillin and clarithromycin to eradicate Helicobacter pylori in patients with H. pylori infection and duodenal ulcer disease.

Ibrahim, J. Adulticidal activity of some Malaysian plant extracts against Aedes aegypti Linnaeus. Trop. What are the uses for rabeprazole? Rabeprazole delayed-release tablets comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get rabeprazole delayed-release tablets refilled. Within 1 hour. 1 23 Median inhibition of 24-hour gastric acidity is 88% of maximum after first dose. Steady state interactions of Rabeprazole and warfarin have not been adequately evaluated in patients. There have been reports of increased INR and prothrombin time in patients receiving a proton pump inhibitor and warfarin concomitantly. Increases in INR and prothrombin time may lead to abnormal bleeding and even death. dexamethasone

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